Complete Vergil's downfall on Son of Sparda difficulty
Acquire all of Vergil's health, Devil trigger and combat upgrades
Complete all missions in Vergil's downfall on the Nephilim difficulty with a SSS rank
Gain a 100% completion rank on all missions in Vergil's downfall (difficulty doesn't matter)
Complete Vergil's downfall
Defeat an Imprisoner
Defeat a Wisp
Complete all missions on the Hell and Hell difficulty
Slay 5,000 Demons
Complete all missions on the Heaven or Hell difficulty
Complete all missions on the Dante Must Die difficulty
Kill 50 enemies using nothing but firearms
Complete all missions on the Son of Sparda difficulty
Purchase all of Dante's combat upgrades
Complete all missions on the Nephilim difficulty with a SSS rank
Upgrade Dante's health to maximum
Kill 100 enemies using nothing but Angel weapons
Upgrade Dante's Devil Trigger to maximum
Complete the final mission on Human, Devil Hunter or Nephilim difficulty
Gain a 100% completion rank on all missions (difficulty doesn't matter)
Defeat Mundus
Complete all of the Secret Missions
Open all of the Secret Doors
Complete Furnace of Souls without taking damage from the furnace
Acquire Kablooey
Navigate the Sky Bridge on Mission 16 without hitting the lasers
Defeat Mundus' spawn
Slay 1,000 Demons
Earn 1,500 Style Bonuses
Acquire Revenant
Acquire Aquila
Spend 10,000 Red Orbs
Acquire the Devil Trigger ability
Help Phineas retrieve his eye
Complete 10 Secret Missions
Free half of the Lost Souls
Complete a level without taking any damage
Complete a level with 2 minutes or less on the clock
Complete a mission with a SSS rank
Acquire Eryx
Reach the end of the descent on Mission 6 having killed all of the enemies
Survive the encounter with the Tyrant
Acquire the Angel Boost ability
Gain a SSS Style Rank during combat
Acquire Osiris
Slay 100 Demons
Acquire Arbiter
Defeat your pursuer
Purchase your first upgrade
Kill 10 enemies by pushing them into the Hurricane ride on Mission 1
Help Vergil open the Vault
Kill 100 enemies using nothing but Demon weapons
Spend 50,000 Red Orbs
Find all of the Keys
Free all of the Lost Souls
Complete Vergil's downfall on Vergil Must Die difficulty
Complete Vergil's downfall on Heaven or Hell difficulty
Complete Vergil's downfall on Hell and Hell difficulty