Lose all credits and die.
Let Player 2 join the game while in the middle of a campaign.
Beat the game with a score of at least 80,000 points.
Score over 100,000 points.
Finish full campaign with a friend!
Discover a secret room.
Finish a single chapter without taking any damage.
Finish any chapter with the help of Player 2.
Kill five enemies in a row.
Kill three enemies in a row.
Beat the game with a score under 80,000 points and the last digit being 0.
Beat the original mode.
Beat the Emperor at the end of the last chapter.
Beat the Magician at the end of the fifth chapter.
Collect your first additional weapon.
Beat the Strength at the end of the fourth chapter.
Beat the Tower at the end of the third chapter.
Beat the Hierophant at the end of the second chapter.
Beat the Judgment at the end of first chapter.
Save a civilian.
Unlock all achievements of The House Of The Dead 2!
Beat the game with a score under 80,000 points and the last digit not 0.
Discover all endings.
Save all civilians throughout the campaign.
Discover all paths available in the game.
Collect all bonuses in a campaign.
Use all weapons.
Collect all creature entries.
Fire off 666 heads!
Devastate Bob's torso as much as possible!
Kill 2137 enemies.
Kill three enemies at the same time.
Finish the whole campaign without taking any damage.
Complete all training challenges with five stars.
Complete all Boss Mode fights with five stars.
Score less than 24,000 points.