Receive 100% synch in ACB and full synch in all missions of the Da Vinci Disappearance.
Complete the Da Vinci Disappearance.
Solve all of Subject 16's puzzles.
Earn 3 gold medals in the Animus Virtual Training Program.
Beat up the 5 thirsty harlequins.
Remove All Borgia Flags in Rome.
Discover the Shrine in the Cloaca Maxima.
Discover the Shrine in Palazzo Laterano.
Discover the Shrine in the Basilica di San Pietro.
Double Assassinate from a parachute.
Jump with the parachute off the top of Castel Sant'Angelo.
Destroy the Bomber.
Steal 5 horses from their riders, while remaining on horseback.
Secure the Apple of Eden.
Complete DNA Sequence 9.
Complete DNA Sequence 8.
Destroy the Naval Cannon.
Discover the Shrine in Il Colosseo.
Throw a Long Weapon, Heavy Weapon, and Smoke bomb more than 10 m at a guard.
Kill a guard with the bag that drops from a lift.
Complete DNA Sequence 7.
Win 10000 florins playing Hazard.
Burn All Borgia Towers.
Complete DNA Sequence 6.
Collect All Feathers.
Complete DNA Sequence 5.
Train a recruit up to the Rank of Assassin.
Destroy the Tank.
Pay 500 florins to an orator, then pickpocket him afterward.
Kill 10 guards with a single arrow storm.
Complete DNA Sequence 4.
Destroy the Machine Gun.
Perform an Execution Streak of 10 kills.
Complete 10 Guild Challenges.
Win the highest bet at the Fights.
Recruit 3 Assassins.
Discover the Shrine in the Catacombe di Roma.
Kill a guard with a broom.
Achieve 100% Synchronization in any Sequence other than Sequence 1.
Throw money in a well.
Replay a Memory.
Complete DNA Sequence 3.
Renovate 5 buildings in the Antico district.
Complete DNA Sequence 2.
Discover the Shrine in the Terme di Traiano.
Access your email in 2012.
Find 1 Artifact in 2012.
Find a secure place to hide and re-enter the Animus.
Complete DNA Sequence 1.
Reach Level 50 (Multiplayer Only).
Get every single bonus at least once (Multiplayer Only).
Kill your target while hidden in a hay bale (Multiplayer Only).
Attempt to access DNA Sequence 9 for the first time.
Get all the Co-op bonuses in 1 session (Multiplayer Only).
Perform a double or triple escape (Multiplayer Only).
Take the lead 10 seconds before the end of a session and go on to win (Multiplayer Only).
Score 750 points or more on a single kill (Multiplayer Only).
During Open Conflict, kill your target and escape (Multiplayer Only).
Kill your target and escape your pursuer in less than 10 seconds (Multiplayer Only).
Complete an entire Session with at least one kill (Multiplayer Only).