Complete DNA Sequence 5.
Throw money in a well.
Complete DNA Sequence 4.
Destroy the Machine Gun.
Discover the Shrine in Il Colosseo.
Achieve 100% Synchronization in any Sequence other than Sequence 1.
Replay a Memory.
Kill a guard with the bag that drops from a lift.
Access your email in 2012.
Recruit 3 Assassins.
Complete DNA Sequence 3.
Renovate 5 buildings in the Antico district.
Complete DNA Sequence 2.
Discover the Shrine in the Terme di Traiano.
Find a secure place to hide and re-enter the Animus.
Escape the hideout.
Complete DNA Sequence 14.
Complete DNA Sequence 11.
Wear the Auditore cape in each city.
Collect all the Feathers.
Unlock all 20 pieces of Subject 16's video.
Complete DNA Sequence 10.
Stun 4 guards at once by throwing sand in their face.
Get all Hidden Blades, Item Pouches and Armor upgrades for Ezio.
Complete DNA Sequence 9.
Sweep 5 guards at once by using a Long Weapon.
Discover the Assassin's Tomb inside Santa Maria della Visitazione.
Complete DNA Sequence 8.
Kill 10 enemies while remaining in conflict without being hit.
Kick a guard while using the Flying Machine.
Discover the Assassin's Tomb inside the Basilica di San Marco.
Complete DNA Sequence 7.
Spend 5000 florins on Courtesans.
Reach 80% of your stronghold's total value.
Discover the Assassin's Tomb inside the Torre Grossa.
Buy a Painting from Florence and Venice.
Perform an Air Assassination on a Poisoned NPC.
Discover the Assassin's Tomb inside the Rocca di Ravaldino fortress.
Tint your clothes with those colors: Wetland Ebony and Wetland Ivory.
Complete training and reenter the Animus.
Complete DNA Sequence 6.
Find the 8 statuettes in Monteriggioni.
Discover the Assassin's Tomb inside Santa Maria del Fiore (The Duomo).
Pickpocket 1000 Florins.
Hide 5 dead bodies in a Bale of Hay.
Complete your first assassination mission for Lorenzo Il Magnifico.
Toss more than 300 florins on the ground.
Sprint for 100 meters.
Discover the Assassin's Tomb inside the catacombs under Santa Maria Novella.
Intercept a Borgia Courrier.
Upgrade a building in the Stronghold.
Unlock a piece of Subject 16's video.
Use your Eagle Vision to scan a Glyph in the environment.
Synchronize 10 View Points.
Complete DNA Sequence 1.
Win a race against thieves.
Defend a woman's honor.
Perform a Leap of Faith from the Top of Florence's Giotto's Campanile.
Enter the Animus 2.0.
Break out of Abstergo.
Be reborn as Ezio Auditore da Firenze.
Attempt to access DNA Sequence 9 for the first time.
Jump with the parachute off the top of Castel Sant'Angelo.
Win the highest bet at the Fights.
Discover the Shrine in the Cloaca Maxima.
Discover the Shrine in Palazzo Laterano.
Discover the Shrine in the Basilica di San Pietro.
Solve all of Subject 16's Puzzles.
Secure the Apple of Eden.
Complete Desmond Sequence 4.
Complete Desmond Sequence 5.
Achieve 100% Synchronization in all Sequences.
Complete the Hagia Sofia challenge level.
Collect all Animus data fragments.
Collect all of Ishak Pasha's memoir pages.
Complete all Bomb Missions.
Control all cities (except Rhodes) simultaneously in the Mediterranean Defense game.
Perform a perfect Den Defense without using the cannon.
Climb Hagia Sofia, from the ground to the pinnacle, in under 25 seconds.
Complete all Faction Creed Challenges from a single faction.
Get your money back from a Templar tax collector.
Have seven trainees reach the rank of Master Assassin.
Kill 5 guards in 5 seconds using only your hidden blades.
Assassinate 50 guards with the hidden blade.
Parachute onto a zipline.
Collect all available books.
Loot 50 dead guards with thief looting.
Have 10 guards poisoned at the same time.
Kill 5 guards with a scaffold after they have been stunned by caltrops.
Craft 30 bombs.
Have one trainee reach the rank of Master Assassin.
Parachute directly from the top of the Galata Tower to the Golden Horn.
Kill three guards simultaneously with only throwing knives.
Kill 5 guards while under the cover of a smoke screen bomb.
Have a guard incapacitate 3 civilians while he's poisoned.
Find and beat up Duccio.
Complete Desmond Sequence 1.
Complete Desmond Sequence 2.
Complete Desmond Sequence 3.
Take the induction leap of faith (The Lost Archive).
Reach the Animus memo (The Lost Archive).
Enter the Animus simulation (The Lost Archive).
Finish memory five (The Lost Archive).
Experience the loop (The Lost Archive).
Find all of the decipher fragments (The Lost Archive).
Break the loop, escape the cycle (The Lost Archive).
Land on a block after falling more than 25 meters (The Lost Archive).
Complete the Animus testing sequence without failing (The Lost Archive).
Make it across the river Styx without failing (The Lost Archive).
Discover the Shrine in the Catacombe di Roma.
Destroy the Naval Cannon.
Destroy the Bomber.
Destroy the Tank.
Burn All Borgia Towers.
Complete 10 Guild Challenges.
Earn 3 gold medals in the Animus Virtual Training Program.
Train a recruit up to the Rank of Assassin.
Remove All Borgia Flags in Rome.
Collect All Feathers.
Find 1 Artifact in 2012.
Perform an Execution Streak of 10 kills.
Throw a Long Weapon, Heavy Weapon, and Smoke bomb more than 10 m at a guard.
Kill a guard with a broom.
Win 10,000 florins playing Hazard.
Receive 100% synch in ACB and full synch in all missions of The Da Vinci Disappearance.
Kill 10 guards with a single arrow storm.
Complete The Da Vinci Disappearance.
Beat up the 5 thirsty harlequins.
Double Assassinate from a parachute.
Steal 5 horses from their riders, while remaining on horseback.
Pay 500 florins to an orator, then pickpocket him afterward.