Unlock all Trophies
Collect all 700 Spider-Man Comic Pages
Complete all XTreme Race challenges
Complete all XTreme Video challenges
Resolve all police deadlocks
Rescue all infected civilians
Clear all car chases
Return all escapees to the police
Unlock all concept art
Complete the game on super hero difficulty
Complete the game on hero difficulty
Complete the game on human difficulty
Defeat Lizard
Collect all magazines
Defeat 1000 enemies
Acquire all upgrades
Collect all audio evidence
Defeat Nattie
Rescue Alistaire Smythe
Defeat the S-03
Collect all hidden Tech Pieces
Collect all Oscorp Manuals
Complete all Oscorp Secret Research Labs
Clear the second fight against the Hunter robots
Chain 10 Web-Rushes in the city
Defeat Felicia
Defeat Scorpion in the city
Immobilize 6 enemies simultaneously with web
Defeat 500 enemies
Defeat Rhino in the sewers
Perform a Web-Rush punch
Defeat the S-02
Defeat Scorpion in quarantine
Defeat Iguana
Defeat 100 enemies by performing Stealth Takedowns
Perform 25 Signature Moves
Destroy a Seeker before it can call a Hunter
Clear the first fight against the Hunter robots
Defeat a Hunter without using your Web-Shooters
Defeat Vermin
Defeat 50 enemies by performing Stealth Takedowns
Achieve a combo streak of 42
Defeat 100 enemies
Save a hostage caught in a petty crime
Defeat Rhino in the city
Defeat the S-01 without touching the ground
Defeat the S-01