Use Heal Us Karma Ability to restore 50% or more health each to 3 players (multiplayer)
Defeat any Guardian with all four players still alive (multiplayer)
Defeat any Guardian without taking damage
Use Heal You Karma Ability to restore 50% or more health to a friend (multiplayer)
Use Health Siphon Power Move to bring a dying friend back to life (multiplayer)
Drop a health pack after a friend requests one (multiplayer)
Defeat the Water Guardian
Perform a timed execution on 10 enemies in one Zone
Trigger every kind of trap in the game
Defeat the Light Guardian
Lose more than 400% health in one Zone without dying
Use Weapon Breaker Power Move with a weapon that's about to shatter
Use Charge Tackle Power Move to knock one enemy into another
Complete a Zone without stopping for more than 30 seconds total
Complete any 5 puzzles without using the hint lever
Use 360 Attack Power Move to strike 4 or more enemies at once
Complete a Zone using only your fists (no weapons)
Complete a Zone without turning on your flashlight
Perform every in-game VO clip for one character
Defeat the Wood Guardian
Defeat 25 Nurses with the Steel Pipe
Use Heal Me Karma Ability to restore 25% or more health
Defeat the Fire Guardian
Make a purchase in Howard's shop
Complete Zone 1
Level up to LVL 2
Create a character
Earn every trophy in the game
Defeat 25 Bogeymen with the Bogeyman's Hammer
Defeat 25 Pyramid Heads with the Great Knife
Use Blood Barrage Karma Ability to kill 5 or more enemies
Use Blood Beam Karma Ability on 5 or more enemies at once
Use Blood Burn Karma Ability to damage 4 different enemy types at once
Use Flash Burst Power Move to kill 5 or more stunned enemies in a row
Use Karma Flip Power Move to flip 8 or more enemies at once
Use Push Force Power Move to knock 8 or more enemies back at once
Earn a 30 or greater timed hit combo
Level up 10 different weapons
Spend over 250,000 MR in Howard's shop
Reach Zone 50
Achieve the LIGHT ending in every Forsaken Room
Achieve the BLOOD ending in every Forsaken Room
Achieve the NEUTRAL ending in every Forsaken Room
Defeat the Earth Guardian
Defeat the Blood Guardian
Defeat the Steel Guardian and complete the game
Reach Zone 100
Complete Valtiel's missions in Zones 1 through 21
Achieve all 6 of the game's endings
Complete your Rooms Checklist 100%
Complete your Artifacts Checklist 100%
Complete your Weapons Checklist 100%
Complete your Broadcasts Checklist 100%
Complete your Notes Checklist 100%
Complete your Bestiary Checklist 100%
Turn all 40 Change Notes to Light at the same time
Turn all 40 Change Notes to Blood at the same time
Level up to LVL 70
Complete the DLC (red) portions of all checklists
Level up to LVL 25
Level up to LVL 50
Defeat 25 Butchers with the Great Cleaver
