The player has completed the game without harvesting any Little Sisters
The player has defeated Atlas
The player has successfully invented all possible ammo types
Collect or Invent 58 Tonics in the Physical, Engineering and Combat tracks
The player has either Harvested or Rescued every possible Little Sister
Fully research the Rosie
The player has become a Big Daddy
Purchased every slot in all four Plasmid and Tonic tracks
Fully upgrade four weapons
The player has broken Fontaine's mind control
The player has defeated Andrew Ryan
The player has successfully completed 50 hacks
Fully research the Houdini Splicer
The player has fully upgraded three weapons
The player has purchased every slot in one of the Plasmid or Tonic tracks
The player has completed Sander Cohen's great masterpiece
The player has fully upgraded two weapons
Hit the jackpot at a slot machine
Take at least one photo in every research group
The player has fully researched the Spider Splicer
The player has fully researched the Thuggish Splicer
The player has restored the forests of Arcadia
The player has successfully invented at least one item
The player has fully researched the Leadhead Splicer
The player has fully upgraded one weapon
The player has acquired at least one weapon upgrade
The player has defeated Peach Wilkins
The player has taken a Research Photo of the highest grade
The player has taken at least one Research Photo of a Splicer
The player has purchased one slot in any Plasmid or Tonic track
The player has defeated the crazed Dr. Steinman
The player has successfully hacked a safe
The player has successfully hacked a security camera
The player has successfully hacked a vending machine
The player has successfully hacked a turret
The player has performed at least one successful hack
The player has successfully hacked a security bot
The player has successfully completed the Welcome To Rapture Level
The player has shocked an enemy in the water
Unlocked all trophies
Acquire all upgrades for all weapons
Max out all possible research
Find every audio diary
Fully research the Bouncer
Fully research the Nitro Splicer
Fully research the Little Sister
Successfully invent at least 100 items
The player has completed the game on the Hard difficulty setting
Fully upgrade five weapons
The player has taken a picture of Sander Cohen's corpse
The player has entered Sander Cohen's personal quarters
Complete the game on Survivor difficulty
Complete the game on Survivor difficulty without using a Vita-chamber
Complete the game on Hard difficulty without using a Vita-Chamber.
Rescued the Little Sister in “The ‘I’ in Team”
Rescued the Little Sister in “The ‘I’ in Team” in under 3:00
Found all collectable Roses in “The ‘I’ in Team”
Rescued the Little Sister in “The ‘I’ in Team” without destroying any Machine Gun Turrets
Rescued the Little Sister in “A Shocking Turn of Events”
The player has rescued the Little Sister in “A Shocking Turn of Events” in under 4:00
Found all collectable Roses in “A Shocking Turn of Events”
Charged up the Ferris Wheel 9 different times in “A Shocking Turn of Events”
Rescued the Little Sister in “Worlds of Hurt”
Rescued the Little Sister in “Worlds of Hurt” in under 15:00, on Medium or higher difficulty
Found all collectable Roses in “Worlds of Hurt”
Rescued the Little Sister in “Worlds of Hurt” using only plasmids, tonics, the wrench, and the research camera, on Medium or higher difficulty
