Win every trophy.
Get every single bonus at least once (Multiplayer Only).
Reach Level 50 (Multiplayer Only).
Kill your target and escape your pursuer in less than 10 seconds (Multiplayer Only).
During Open Conflict, kill your target and escape (Multiplayer Only).
Get all the Co-op bonuses in 1 session (Multiplayer Only).
Score 750 points or more on a single kill (Multiplayer Only).
Perform a double or triple escape (Multiplayer Only).
Kill your target while hidden in a hay bale (Multiplayer Only).
Complete the Da Vinci Disappearance.
Steal 5 horses from their riders, while remaining on horseback.
Double Assassinate from a parachute.
Beat up the 5 thirsty harlequins.
Kill 10 guards with a single arrow storm.
Win 10000 florins playing Hazard.
Kill a guard with the bag that drops from a lift.
Throw a Long Weapon, Heavy Weapon, and Smoke bomb more than 10 m at a guard.
Remove All Borgia Flags in Rome.
Solve all of Subject 16’s puzzles.
Train a recruit up to the Rank of Assassin.
Jump with the parachute off the top of Castel Sant'Angelo.
Collect All Feathers.
Destroy the Tank.
Destroy the Naval Cannon.
Discover the Shrine in the Cloaca Maxima.
Destroy the Bomber.
Discover the Shrine in the Basilica di San Pietro.
Secure the Apple of Eden.
Complete DNA Sequence 9.
Complete DNA Sequence 8.
Complete DNA Sequence 7.
Burn All Borgia Towers.
Win the highest bet at the Fights.
Discover the Shrine in Palazzo Laterano.
Complete 10 Guild Challenges.
Complete DNA Sequence 6.
Pay 500 florins to an orator, then pickpocket him afterward.
Complete DNA Sequence 5.
Renovate 5 buildings in the Antico district.
Kill a guard with a broom.
Complete DNA Sequence 4.
Destroy the Machine Gun.
Recruit 3 Assassins.
Earn 3 gold medals in the Animus Virtual Training Program.
Perform an Execution Streak of 10 kills.
Find 1 Artifact in 2012.
Access your email in 2012.
Achieve 100% Synchronization in any Sequence other than Sequence 1.
Throw money in a well.
Replay a Memory.
Complete DNA Sequence 3.
Discover the Shrine in Il Colosseo.
Discover the Shrine in the Catacombe di Roma.
Complete DNA Sequence 2.
Discover the Shrine in the Terme di Traiano.
Find a secure place to hide and re-enter the Animus.
Complete DNA Sequence 1.
Attempt to access DNA Sequence 9 for the first time.
Take the lead 10 seconds before the end of a session and go on to win (Multiplayer Only).
Complete an entire Session with at least one kill (Multiplayer Only).
Receive 100% synch in ACB and full synch in all missions of the Da Vinci Disappearance.