Defeat Doctor Octopus in Chapter 1
Defeat Green Goblin in the Prologue.
Collected all other Marvel Heroes Omega trophies.
Defeat The Hood in Chapter 2.
Defeat Elektra in Chapter 3.
Defeat The Kingpin in Chapter 4.
Defeat Juggernaut in Chapter 5.
Defeat Magneto in Chapter 6.
Defeat Mister Sinister in Chapter 7.
Defeat Doctor Doom in Chapter 8.
Complete Chapter 9 in Story Mode.
Loot 1,000,000 Credits.
Visit Six Different Headquarters.
Defeat a Training Room Target Dummy.
Complete 14 Different Operations.
Rescue 100 civilians in Midtown Patrol.
Reach level 60 with any hero.
Explore all of the Treasure Rooms in each chapter of Story Missions.
Loot 100 Artifacts.
Complete 50 Legendary Quests.
Apply a Modification to an Artifact.
Open 50 Bounty Chests in Operations.
Complete the Super Heroic Trial with any hero.
Level any vendor to level 10.
Fully upgrade a Legendary Item.
Collect any 100 Relics of the same type.
Defeat 150 Super Villains in Midtown Manhattan.
Loot a Cosmic Medallion.
Defeat 7 Different Super Villains in their Showdowns.
Complete 24 different Special Events in Story Mode.
Prestige any Hero.
Complete the Cosmic Trial with any hero.
Prestige any Hero twice.
Get Five Heroes to Level 60.
Defeat 10 different members of the Sinister Six.
Alone, defeat Shocker in under 50 seconds upon entering the Abandoned Subway Operation.
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