Fully upgrade three weapons.
Either Harvest or Rescue every Little Sister in the game.
Purchased every slot in all four Plasmid and Tonic tracks.
Fully upgrade two weapons.
Fully upgrade one weapon.
Successfully complete 50 hacks.
Purchased every slot in one of the Plasmid or Tonic tracks.
Successfully invent at least one item.
Acquire at least one weapon upgrade.
Take a Research Photo of the highest grade.
Take at least one Research Photo of a Splicer.
Purchase one slot in any Plasmid or Tonic track.
Successfully hack a security camera.
Successfully hack a safe.
Successfully hack a turret.
Successfully hack a vending machine.
Perform at least one successful hack.
Successfully hack a security bot.
Successfully complete the Welcome To Rapture Level.
Shock an enemy in the water.
Rescued the Little Sister in &The 'I' in Team& in under 3:00
Complete the game on Hard difficulty without using a Vita-Chamber.
Rescued the Little Sister in &The 'I' in Team&
Complete the game without harvesting any Little Sisters.
Found all collectable Roses in &The 'I' in Team&
Rescued the Little Sister in &A Shocking Turn of Events&
The player has rescued the Little Sister in &A Shocking Turn of Events& in under 4:00
Found all collectable Roses in &A Shocking Turn of Events&
Charged up the Ferris Wheel 9 different times in &A Shocking Turn of Events&
Rescued the Little Sister in &Worlds of Hurt&
Rescued the Little Sister in &Worlds of Hurt& in under 15:00, on Medium or higher difficulty
Found all collectable Roses in &Worlds of Hurt&
Rescued the Little Sister in &Worlds of Hurt& on medium or higher difficulty using only the wrench.
Rescued the Little Sister in &The 'I' in Team& without destroying any Machine Gun Turrets
Complete the game on the hardest difficulty setting.
Hit the jackpot at a slot machine.
Fully research the Leadhead Splicer.
Take at least one photo in every research group.
Acquire all upgrades for all weapons.
Find every audio diary.
Fully upgrade four weapons.
Fully upgrade five weapons.
Fully research the Thuggish Splicer.
Fully research the Spider Splicer.
Fully research the Bouncer.
Fully research the Nitro Splicer.
Fully research the Rosie.
Fully research the Little Sister.
Max out all possible research.
Successfully invent at least 100 items.
Successfully invented all possible ammo types.
Collect or Invent 53 Tonics in the Physical, Engineering and Combat tracks.
Fully research the Houdini Splicer.
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