Complete Chapter One of the story campaign.
Perform a 4-Turtle Turtle Power Knock Out.
Knock out 100 enemies while playing as Leonardo.
Knock out 100 enemies while playing as Raphael.
Achieve Level 3 with Raphael's Iron Fists.
Use Raphael's Counter Submissions 25 times.
Knock out 25 enemies with special attacks.
Perform a double counter 25 times.
Perform a special counter 25 times.
Perform a team attack 50 times.
Use a Turtle Power Knock Out on 100 enemies.
Perform a Shell Shock attack 100 times.
Knock out 25 enemies using a stealth attack.
Achieve Level 3 with Leonardo's Blade Staff.
Perform a 99-hit combo.
Perform 12 attack variations in a single combo.
Complete all Challenge levels.
Complete round 20 in Survival mode.
Complete all Arcade levels.
Complete Chapter Two of the story campaign.
Complete Chapter Three of the story campaign.
Complete Chapter Four of the story campaign.
Shoulder run off 100 enemies while playing as Leonardo.
Unlock Classic Mode by reaching level 10.
Knock out 100 enemies while playing as Donatello.
Achieve Level 3 with Donatello's Gravity Gauntlet.
Hit 25 enemies with Donatello's special pose attacks.
Knock out 100 enemies while playing as Michelangelo.
Achieve Level 3 with Michelangelo's Kusarigama.
Taunt 100 enemies with Michelangelo's special taunt.
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