Earn all chain reaction diamond medals in story mode
Earn all chain reaction gold medals in story mode
Earn all diamond medals for the DNA chain defense
Reach a diamond rating in the 5 challenges
Earn all diamond medals in story mode
Reach a gold rating in the 5 challenges
Earn all gold medals in story mode
Earn all life diamond medals in story mode
Earn all life gold medals in story mode
Buy at least one point in every skill
Reach the maximum levels for all skills
Earn all time diamond medals in story mode
Earn all time gold medals in story mode
Complete the game with both difficulties set to hard
Reach the last wave difficulty in the 5 challenges
Be awarded with an extra chain reaction
Destroy 6 critical cubes in any sample of the story mode
Complete chapter 1
Complete chapter 2
Complete chapter 3
Complete chapter 4
Complete chapter 5
Complete sample 12 without touching a single sticky web
Complete sample 14 without slowing the chain
Complete sample 17 without being poisoned once by toxins
Complete sample 21 without colliding with a single flagellate pathogen
Complete sample 25 without using the EMP
Complete sample 8 without destroying a single bloated cell
Be awarded with 20 macroshots in a single level
Complete the game with no upgrade for cube speed
Complete the game with no life upgrade
Complete the game with no shield size reduction
Complete the game in hard puzzle difficulty
Complete the game in hard shooter difficulty
Destroy one virus pathogen in sample 11, 12 or 13
19181
20766
21345
1142
216
1092
914
132
44
2