Replay a Memory.
Achieve 100% Synchronization in any Sequence other than Sequence 1.
Complete DNA Sequence 7.
Train a recruit up to the Rank of Assassin.
Complete DNA Sequence 8.
Burn All Borgia Towers.
Complete DNA Sequence 9.
Secure the Apple of Eden.
Complete DNA Sequence 5.
Complete DNA Sequence 4.
Destroy the Machine Gun.
Destroy the Bomber.
Destroy the Tank.
Recruit 3 Assassins.
Complete DNA Sequence 3.
Renovate 5 buildings in the Antico district.
Discover the Shrine in the Terme di Traiano.
Complete DNA Sequence 2.
Find a secure place to hide and re-enter the Animus.
Attempt to access DNA Sequence 9 for the first time.
Complete DNA Sequence 1.
Complete the Da Vinci Disappearance.
Get every single bonus at least once (Multiplayer Only).
Discover the Shrine in the Cloaca Maxima.
Perform a double or triple escape (Multiplayer Only).
Throw a Long Weapon, Heavy Weapon, and Smoke bomb more than 10 m at a guard.
Win 10000 florins playing Hazard.
Receive 100% synch in ACB and full synch in all missions of the Da Vinci Disappearance.
Kill 10 guards with a single arrow storm.
Solve all of Subject 16's puzzles.
Get all the Co-op bonuses in 1 session (Multiplayer Only).
Beat up the 5 thirsty harlequins.
Double Assassinate from a parachute.
Steal 5 horses from their riders, while remaining on horseback.
Kill a guard with the bag that drops from a lift.
Discover the Shrine in Il Colosseo.
Pay 500 florins to an orator, then pickpocket him afterward.
Discover the Shrine in the Catacombe di Roma.
Complete DNA Sequence 6.
Score 750 points or more on a single kill (Multiplayer Only).
Reach Level 50 (Multiplayer Only).
Earn 3 gold medals in the Animus Virtual Training Program.
Kill a guard with a broom.
Complete 10 Guild Challenges.
Destroy the Naval Cannon.
Discover the Shrine in the Basilica di San Pietro.
Remove All Borgia Flags in Rome.
Collect All Feathers.
Find 1 Artifact in 2012.
Perform an Execution Streak of 10 kills.
Jump with the parachute off the top of Castel Sant'Angelo.
During Open Conflict, kill your target and escape (Multiplayer Only).
Win the highest bet at the Fights.
Discover the Shrine in Palazzo Laterano.
Access your email in 2012.
Complete an entire Session with at least one kill (Multiplayer Only).
Kill your target while hidden in a hay bale (Multiplayer Only).
Take the lead 10 seconds before the end of a session and go on to win (Multiplayer Only).
Kill your target and escape your pursuer in less than 10 seconds (Multiplayer Only).
Throw money in a well.
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