Beat 2 levels in a row without picking up any hearts
Have 4 or more soul hearts at one time
Obtain all trophies
Beat 2 levels in a row without taking damage
Make 3 deals with the devil in one run
Beat the Womb for the first time
Beat the Basement 40 times
Beat the Caves 30 times
Beat the Depths 20 times
Beat the Basement/Cellar without taking damage
Beat the Caves/Catacombs without taking damage
Beat the Depths/Necropolis without taking damage
Beat the Womb/Utero without taking damage
Beat all 20 Challenges
Collect 2 of either Roid Rage, The Virus, Growth Hormones, Experimental Treatment, or Speed Ball
Kill Mom
Kill Mom using the Bible
Kill Mom's Heart 3 times
Kill Mom's Heart 5 times
Kill Mom's Heart 8 times
Kill Mom's Heart 9 times
Kill Mom's Heart 10 times
Have 7 or more max red hearts at one time
Kill Mom's Heart 11 times
Kill all 7 sins
You are the best!
Collect all items and unlock all secrets and endings
Beat Greed Mode with Azazel
Complete ??? 3 times
Beat Hard mode as Lazarus without losing a life
You are just like your father...
The other side is calling...
Beat everything in Hard Mode as every character
. . .
Hold 55 or more pennies at one time
41149
1956
252
2161
