Complete a mission with a SSS rank

Free half of the Lost Souls

Complete the final mission on Human, Devil Hunter or Nephilim difficulty

Defeat Mundus

Help Vergil open the Vault

Spend 10,000 Red Orbs

Earn 1,500 Style Bonuses

Acquire Osiris

Slay 100 Demons

Slay 1,000 Demons

Gain a SSS Style Rank during combat

Acquire Kablooey

Defeat Mundus' spawn

Acquire the Angel Boost ability

Purchase your first upgrade

Defeat your pursuer

Acquire Arbiter

Survive the encounter with the Tyrant

Acquire Eryx

Acquire Revenant

Acquire Aquila

Acquire the Devil Trigger ability

Help Phineas retrieve his eye

Kill 100 enemies using nothing but Angel weapons

Kill 100 enemies using nothing but Demon weapons

Kill 10 enemies by pushing them into the Hurricane ride on Mission 1

Reach the end of the descent on Mission 6 having killed all of the enemies

Kill 50 enemies using nothing but firearms

Complete a level with 2 minutes or less on the clock

Complete a level without taking any damage

Complete all missions on the Dante Must Die difficulty

Complete all missions on the Heaven or Hell difficulty

Complete all missions on the Son of Sparda difficulty

Complete all missions on the Nephilim difficulty with a SSS rank

Complete all of the Secret Missions

Complete 10 Secret Missions

Gain a 100% completion rank on all missions (difficulty doesn't matter)

Complete all missions on the Hell and Hell difficulty

Open all of the Secret Doors

Spend 50,000 Red Orbs

Navigate the Sky Bridge on Mission 16 without hitting the lasers

Slay 5,000 Demons

Upgrade Dante's health to maximum

Upgrade Dante's Devil Trigger to maximum

Complete Furnace of Souls without taking damage from the furnace

Find all of the Keys

Purchase all of Dante's combat upgrades

Free all of the Lost Souls