Kill 2500 enemies.
Kill 10 'Ard Boyz.
Fire the Psychic Scourge.
Collect 10 Servo Skulls.
Kill 500 enemies using Ranged weapons.
Retrieve the Power Source.
Get 100 Headshots.
Kill 25 enemies with Ground Pound.
Kill 500 enemies using Melee weapons.
Kill 25 Ork Nobs.
Destroy the Orbital Gun.
Multi-kill -- 2 enemies with 1 Stalker-Pattern bolter shot.
Fight your way to the crashed Rok.
Multi-kill -- 5 enemies with 1 Frag grenade.
Reunite with your Space Marine brothers.
Kill 100 enemies.
Achieve 100% Synchronization in any Sequence other than Sequence 1.
Replay a Memory.
Secure the Apple of Eden.
Complete DNA Sequence 9.
Complete DNA Sequence 8.
Complete DNA Sequence 7.
Burn All Borgia Towers.
Train a recruit up to the Rank of Assassin.
Complete DNA Sequence 5.
Destroy the Bomber.
Destroy the Tank.
Complete DNA Sequence 4.
Destroy the Machine Gun.
Recruit 3 Assassins.
Complete DNA Sequence 3.
Renovate 5 buildings in the Antico district.
Complete DNA Sequence 2.
Discover the Shrine in the Terme di Traiano.
Find a secure place to hide and re-enter the Animus.
Complete DNA Sequence 1.
Attempt to access DNA Sequence 9 for the first time.
Purchase any 1 accessory for any 1 uniform
Purchase any 1 uniform
Reached Level 51
Complete all maps in "Hunter" game mode on Rookie or Normal difficulty
Purchase both upgrades for all gadgets
Purchase both upgrades for any 1 gadget
Take down Tom Reed
Complete Single Player Story "White House" on any difficulty
Allow Tom Reed to live
Complete Single Player Story "Downtown District" on any difficulty
Complete Single Player Story "Michigan Ave. Reservoir" on any difficulty
Complete Single Player Story "Third Echelon HQ" on any difficulty
Discover Anna Grimsdottir's dark secret