The King of Action is back and ready to kick some ass! Duke's original nemesis, Proton, is back and has unified all those who have opposed Duke in the past. The Earth Defense Force attempts to ensure the Earth's continued security by transporting Duke into the future. Ironically, just moments after Duke's departure, Proton launches a devastating attack on Earth!

Get the full Duke experience as you guide him through a world invaded by aliens. Save earth and of course all babes with blazing guns....or sometimes just a well placed kick of your mighty boot.