Complete all the Brain Wars missions on Immune Badass difficulty.
Complete all the Intestine Assault missions on Immune Badass difficulty.
Read all Help Guides and the Credits section.
Complete all Veins Campaign missions on Immune Badass difficulty.
Score 5000 kills in Brain Wars Immune Badass Survival mode.
Score 5000 kills in Intestine Assault Immune Badass Survival mode.
Score 5000 kills in Veins Campaign Immune Badass Survival mode.
Gather 60 Golden medals in Brain Wars mode.
Gather 60 Golden medals in Intestine Assault mode.
Gather 60 Golden medals in Veins Campaign mode.
Destroy 500 powerups of any kind.