There are three possible endings, depending on how the Little Sisters were treated.
If more than one Little Sister was harvested, the "bad" ending will play.
If no more than one Little Sister was harvested, but the rest were rescued, the "good" ending will play.
Rescue all the Little Sisters in the game except for one that is harvested to see the third ending.
Big Daddy Vs Big Daddy
In certain areas there will be 2 Big Daddy's at one time, one will have a Little Sister and one won't.
1. Use the hypnotize Big Daddy Plasmid on the one that does not have a Little Sister.
2. Attack the Big Daddy with the Little Sister and the other Big Daddy will start to protect you by attacking.
3. Watch the health of both Big Daddy's and when they get close to dying start using your frag grenades to finish both of them off.
Chompers Dental Key
The key to Chompers Dental in the Medical Pavilion is acquired by using Telekinesis through the broken window to the left of the door. There should be a corpse hanging over the broken window. The key should be grabbed with Telekinesis because it is hanging on a wall on the other side of the window. You can get Telekinesis in an area near here. You will need to get that first, but do not follow the arrow back to the rubble that you need to get rid of until you explore Chompers Dental. There is a safe and other good items to be found inside. Note that both Telekinesis and Chompers Dental are near where you find the shotgun.
Consistent Big Daddy Kill Strategy
This works when you have an upgraded Crossbow and Upgraded Electro-Bolt. I haven't tried with the simplest versions, but I assume it will just take more Crossbow Bolts.
When you have The Electro-Bolt Plasmid equipped, and the Crossbow with the TRAP BOLT, you can easily use this strategy to kill a Big Daddy. When you encounter a Big Daddy, it's best to be in a place where you can move around.
First you fire a Trap Bolt and start backing up cause it comes at you fast. Immediately after you fire, you switch to Electro-Bolt and zap it, then immediately switch back to the crossbow.
If your Plasmid is strong enough, he shouldn't have enough time to recover before you shoot him again. Keep moving, though, cause sometimes he may get a running start before you stun him again.
It took me one clip of a crossbow, but it will be different for everybody. You may have to take a hit, but it's the fastest way to take the Big Daddy down.
Defeating Atlas Fontaine
This is the final Boss and he has three different styles of attacks:. Flame Plasmid Form, Ice Plasmid Form, and Electric Plasmid Form. The easiest way to defeat him in the first part is to use your Ice Plasmid and freeze him. Then, switch to your Telekinesis Plasmid. Grab an explosive tank and throw it at him. Also, if desired, just use your telekinesis. He is very predictable if you are far away from him. Wait for him to throw a fire ball at you then move out of the way. He will continue to run past you. Use this chance to fire the machine gun, which does the most damage to him. Once he goes back to his chamber to gain his life back, change to the Flame Plasmid and get ready for some bots. Once he starts his routine of fire and run, blast again him with the Flame Plasmid . The more you blast him, the faster he loses life. Continue to use the machine gun while he is aflame. He will now go back to his chamber one last time. He now has electrical powers. Keep your Flame Plasmid ready. This time, shoot him with the Flame Plasmid and he will run for the water. Once he jumps in the water and comes back out, hit him with it again. Be aware that there are splicers all over as well. Also set them ablaze to get some extra life. There are many different ways to defeat him but this seemed to be the easiest.
The easiest way to defeat Atlas is to make sure that you have the fully upgraded shotgun and the Decoy ability. After you drain his Adam, drop a decoy and while Atlas is attacking it, use the shot gun. After you have used all four rounds immediately cast Decoy again, reload your shotgun, then begin shooting him again. Repeat this until you have to drain his Adam. Once again, reload your shotgun and Plasmids before you drain his Adam. Then start over using Decoy and the shotgun. Use Health Packs as needed and ignore any Splicers in the area, as they will be paying attention to your Decoy just like Atlas.
Defeating Big Daddies
Once you have obtained the crossbow and at least five Trap Bolts, it will be very easy to take down a Big Daddy. Face a wall and stand about three feet away. Make sure it is not something that the bolts can bounce off of, and also make sure you have a nice ten foot long straight wall. Once you are better skilled at this technique, you can try for shorter lengths if desired. Point straight ahead and fire out a bolt. Take about two steps to the left or right, depending on which way the Bid Daddy is, and at your location, and fire another. Fire all five bolts out, then shoot the Big Daddy once with anything. If done correctly, it will run through the line of traps, taking enough health down so he can be killed with a few shots of your weapon of choice. Note: This may not work in an open area because Big Daddies strafe frequently. If you have the damage increase for the crossbow, it will only take three or four bolts to kill him. Do not crouch while setting up the traps. If the Big Daddy walks another way and gets out of sight, you may need to go back to get him. If you do get him, you can crouch under the set traps. An easy way to trigger bolt traps is to pick up something with Telekinesis and drag the object through it
Get your shotgun fully upgraded (power to the people stations, rate of fire, and damage upgrades), then just use your old 00 buck. After you have killed them, you can get the Little Sister and all the money they had on them. This can result to no to to very little damage from Big Daddies. Aim for the head to cause more damage. Note: This was done under the Easy difficulty setting.
After you have acquired the Security Bullseye Plasmid, set off an alarm either by hacking or being spotted by a security camera. Then, throw the Security Bullseye at the Big Daddy. You may have to do this twice depending on how much health the Big Daddy has when starting out. Try to avoid the battle because the crossfire and exploding bots will damage your health. The only problem with this technique is that once the Big Daddy is taken down, the bots will come after you. Be prepared to either run and hide, or fight them off.
Defeating Frank Fontaine
To defeat Frank Fontaine very fast, when you first enter the room hit him with the tool the Little Sisters gave you. Fight him when he throws you off. Once he is back on the bed, run up and hit him again with the tool to drain his Adam. This works a lot faster due to him only have four or five jars of Adam to drain, and the fights are not very long afterwards.
Defeating Peach Wilkins
When the dark cloud envelopes the icy battlefield upon which you must face Peach Wilkins, save the game and locate the hostile turret at the end of the room when the cloud clears. Load the game and run to it before the cloud clears, so that you can quickly freeze or shock it. Then, hack it so it shoots your enemies. Crouch down by the area to your right when facing the turret. There are a few barriers here to protect you from enemy fire. However, to avoid damage by Wilkins' grenades, keep Telekinesis as your active Plasmid. He will avoid the turret's fire, but as long as you stay behind the barriers by the turret he will stay at a safe distance. This gives you time to calmly return his grenades using Telekinesis until he dies. The turret will take out most of the Splicers. This method makes things much easier because it eliminates the hectic "run around and whack people with the wrench" strategy that is otherwise your only option. That turret if not used as an ally would probably be the main cause of your death, along with the bots triggered by the security camera. By hiding near the allied turret however, you also hide from the camera's view.
When fighting a Rosie, use armor piercing rounds from the machine gun or pistol. For a more effective way of killing, launch frag grenades and run out a door. The Rosie will follow you, fire proximity mines at the door, and when it walks through it will be damaged or destroyed.
While in levels that have more than one Little Sister in them, you may see a Rosie roaming the level alone. The following should only happen if you have already harvested or saved at least one, but not all the Little Sisters in that level. The lone Rosie will walk up to one of the many holes in the walls through which the girls crawl through. It will bang on the metal and wait. Then it will help a Little Sister jump down from the opening. The girl will then lead the Rosie throughout the level. Therefore, when hunting these formidable enemies, do not attack or ignore a Rosie if it walks alone (as long as in the pause screen it says that there is still at least one Little Sister remaining). Rather, follow it. Wait for it to summon a Little Sister out of the wall, then attack it using whatever strategy suits you. If you attack it when it's alone you will not get to harvest or save any Little Sister as a reward for killing it.
Defeating Security Robots
If you are up against a stationary security robot (RPG, etc.), use Telekenesis to grab a crate or pallet. Hold it in front of you until you can find a place to hide and plan what to do next. The item you hold up will block some attacks.
From the start you will have a wrench and the Electric Bolt Plasmid at your disposal. Using these is rapid succession against most Splicers can often result in an efficient, quick kill. First, shock the Splicer. Before the convulsion ends, switch out the wrench, aim high, and hit the Splicer over the head. The most efficient way of eliminating the agile Spider Splicers however is to unleash a few clips of anti-personnel ammo, preferably from the machine gun.
When you find any slot machine, use Incinerate Plasmid to corrupt the machine. You will nearly always win money when you use the burnt out machine.
Enemy Ignores You
Just after receiving The ADOM extractor from the Little Sister, do not take the elevator to the last fight. Instead, go through the rooms you missed along the way. Cameras , turrets, Splicers, and Big Daddies will not see you, and electric trap bolts will not hurt you.
Facing Sander Cohen Twice
Do not kill Cohen after completing his "masterpiece". When you go to the Olympus Heights and reach the area with multiple levels (not Fontaine's house for the poor) to get the second half of the antidote, visit one of the apartments on the first level (to your right upon entrance). This is Cohen's apartment. He tells you not the disturb the dancers. Just "knock over" the record player and deal with the upset duo. Cohen himself will then come down to kill you. He can be dispatched then. Go upstairs in his apartment (the door to your right upon entering his place), you will receive the achievement for entering his apartment and reach a Power To The People machine. Now, Sander Cohen will not stay dead. If you pickpocket his corpse, you will get his Muse key. When you get back on the Bathysphere, go to Fort Frolic. You can access the Muse (the chained up display) for some decent items, especially if you need first aid kits. Using your chemical thrower (and perhaps anything else) walk to the "masterpiece". Add Napalm and Criticism together and torch the awful thing. The area will turn red and Cohen will appear for round two. He is a little harder to kill this time and fights like a Houdini splicer. Pickpocket him again for the same items as last time (including the key for the already opened Muse). He is permanently dead.
The various alcoholic beverages (for example, Arcadia Merlot, Old Tom Whiskey, etc.) scattered throughout the game, while normally used to recover health, can be turned into Molotov cocktails similar to those used by the "Nitro Splicer" enemy. To do this, one needs a source of flame, such as the chemical thrower, the "Incinerate!" Plasmid, or an environmental source. Ignite the alcohol bottle, pick it up with the "Telekinesis" Plasmid, and throw at your enemy of choice.
Pac Man Reference
In the Arcadia level, you will find a place that appears to be a bar. Search around a bit and you will see a block of cheese, followed by holes. The cheese is cut like Pac-Man himself. There are holes next to it, none of which can be gun shots. If you shoot the floor with any weapon you have, the marks will not match.
Reaching Fontaine's Penthouse
The code to get to Fontaine's penthouse is from the diary: "5744".
Restore Hacked Robot's Health
After hacking a robot, it will begin firing at your enemies. If the robot gets hit it will begin to lose health, catch on fire, and eventually blow up. To stop this from happening, deactivate the robot ( press A while pointing at the robot), then reactivate it a few seconds later. This should make the robot have full health again.
Save Game Recommendation
After becoming a Big Daddy, make a new saved game. At this point you are near the end of the game. If you missed something you can go to the bathysphere and explore Rapture again, but also you are a Big Daddy now so the splicers will not harm you, security cameras will not set off alarms, etc.
Save the game before you start playing. Just keep reloading the game until you hit it.
Alternate Endings ( Contains Spoilers )
|Unlockable||How to unlock|
|Ending 1||Save all the Little Sisters you encounter in the game|
|Ending 2||Ending B Harvest all the Little Sisters you encounter in the game|
|Ending 3||Rescue all the Little Sisters in the game but harvest one.|
Big Daddy Battle
In order to do this, you need the Hypnotize Big Daddy Plasmid and the Natural Camouflage Tonic. All you have to do is use the Hypnotize Big Daddy Plasmid on a Big Daddy so that he thinks you're a Little Sister and protects you. Now here's the fun part - simply find and attack another Big Daddy and your Big Daddy will attack it to protect you.
Big Daddy Kills
When fighting a Big Daddy, use armor-piercing rounds, as they will deal considerable damage compared to regular rounds.
Big Daddy Kills II
Once you get the Grenade Launcher and the Proximity Mines, this technique can be employed. Find a red fuel tank (all over the place), and cover it with about 6 Proximity Mines or so. Next, use Telekinesis to lift the massive explosive device and hurl it at a Big Daddy. This deals massive damage, leaving you with minimal effort to finish the job. Just be careful not to have the bomb blow up before you get there. (The launcher upgrade that deals no damage to you is a great thing to have just in case.)
Big Daddy Kills III
Here's another technique to take out Big Daddies. Use the Electric Buck on your Shotgun, alternating between the buck and using the Electro Bolt Plasmid every few seconds (which will shock and freeze him in addition to dealing damage). This technique is especially useful on Bouncer class Big Daddies.
Big Daddy Kills IV
Once you've obtained the Dart Gun, you can try this technique. All that's required is Electrical Trap Darts (4-6 per Big Daddy). Take your 4-6 Trap Darts and line them down a hall or near where you can see a Big Daddy, making sure the path he'll take towards you is amply covered. Once that's done, shoot at the Big Daddy to get his attention and keep him running towards you. He'll run into each dart and kill himself.
Big Daddy Kills V
If you have Trap Bolts for your Crossbow, you can execute this technique to kill Big Daddies easily. Give yourself about 20 feet (in-game, of course) and shoot your Trap Bolts so they hang between you and the location of the Big Daddy you want to kill. Then shoot a round with another weapon at the Big Daddy to anger it so it comes towards you. It will stumble across the Trap Bolts you've shot and die, since it only takes two of them to take one down.
Big Daddy Kills VI
Here's another easy method to kill Big Daddies easily. Try using Electric Gel in the Chemical Thrower. It takes about 3/4 of a tank, but the Big Daddy won't be able to move as you shoot and kill him.
BioShock 2 Trailer
To unlock the BioShock 2: Sea of Dreams trailer, available only on the PlayStation3 version of the game, complete the game once through in its entirety.
Easy Splicer Kills
For easy Splicer kills, simply use Telekinesis on one to hurl its body at others in the vicinity. This method usually results in a one-hit kill and is especially useful against higher-level Splicers.
Free Health Packs
While you can buy health packs at health stations for $10, you can get them for free by simply smashing the machines with your wrench. After a few hits, between 1-3 health packs should lie on the floor for you to grab, for free.
Good Ending / Bad Ending
There are two possible endings for BioShock that depend on how you treated little sisters throughout the game. If you choose to "harvest" more than one little sister, you will get the bad BioShock ending. If, however, you "harvest" no more than one little sister but "rescue" the others, you will get the good BioShock ending.
Power To The People Station Locations
Listed below are all twelve Power to the People stations, which can be used to garner weapon upgrades.
Apollo Square - Hestia (4th Floor)
Arcadia - Tree Farm
Farmer's Market - Winery Cellar (Bottom Floor)
Fort Frolic - Sinclair's Spirits (Basement)
Fort Frolic - Le Marquis D'Epoque
Hephaestus - Across from Gatherer's Garden
Hephaestus - Kyburz's Office
Neptune's Bounty - Freezer (Bottom Floor)
Olympus Heights - Fontaine's Apartment (opposite side)
Olympus Heights - Sander Cohen's Private Chambers
Pt. Prometheus - Atrium
Pt. Prometheus - Optimized Eugenics
The following works with both the Crossbow and the Grenade Launcher. While shooting either, you can rapidly reload by pressing the left trigger, then quickly after pressing the right trigger. This will allow you to start shooting without having to wait longer (several seconds) for your weapon to reload. This is especially useful against powerful enemies like Big Daddies.
About halfway through the game, you meet Sander Cohen, this crazy artist dude. When you finish the level, you can just leave him or kill him. If you kill him at that point, you can't get one of the Achievements "Find Cohen's Room." A while later you will stumble onto Cohen's apartment. If he's alive, two Splicers will be dancing in the main room, with Cohen watching from his locked private room. Kill the Splicers and then Cohen comes out to fight you, thus unlocking the door and allowing you to earn the Achievement.
Security Drone Manipulation
Use a blast of the Electric Shock Plasmid to temporarily disable security drones before you do anything else in a room. Then, run up to them within five seconds and hack them! You can hack while the game is on virtual "pause." You'll have security drones on your side for the rest of the time you are in a fight after doing this.
While using the Telekinesis Plasmid, you can drop the item you are holding instead of throwing it across the room. To do this you must have an item currently being held. Pick up any item, with the Telekinesis Plasmid selected. Using the LT button, keep holding the item, and dont let go of the LT button.
When youre ready to drop the item, press the RB button to open your weapons menu, and in the transition of the weapons menu opening, let go of the LT button. Choose your weapon and the item will drop safely to your feet. If done correctly, the item falls at your feet, instead of being thrown, which makes the item easier to find when you need it.
A simpler way to drop the item you're holding is to just hit 'X'. So, with the Telekinesis Plasmid armed, hold LT to TK something to you. While it's 'in your face', press X to drop it on the ground. No need to switch to weapons.
In levels if you shoot a splicer and that splicer lands on its back its eyes and mouth will stay open and its hand will start waving at you. This doesn't happen often and the splicer has to land just right. Mostly female splicers wave.